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Remote-sensing data for protected areas in northern Togo, obtained in three different years (2007, 2000, and 1987), were used to assess and map changes in land cover and land use for this drought prone zone. The normalized difference vegetation index (NDVI) was applied to the images to map changes in vegetation. An unsupervised classification, followed by classes recoding, filtering, identifications, area computing and post-classification process were applied to the composite of the three years of NDVI images. Maximum likelihood classification was applied to the 2007 image (ETM+2007) using a supervised classification process. Seven vegetation classes were defined from training data sets. The seven classes included the following biomes: riparian forest, dry forest, flooded vegetation, wooded savanna, fallows, parkland, and water. For these classes, the overall accuracy and the overall kappa statistic for the classified map were 72.5% and 0.67, respectively. Data analyses indicated a great change in land resources; especially between 1987 and 2000 probably due to the impact of democratization process social, economic, and political disorder from 1990. Wide-scale loss of vegetation occurred during this period. However, areas of vegetation clearing and regrowth were more visible between 2000 and 2007. The main source of confusion in the contingency matrix was due to heterogeneity within certain classes. It could also be due to spectral homogeneity among the classes. This research provides a baseline for future ecological landscape research and for the next management program in the area.