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Insect pests, diseases and other biotic agents have considerable impacts on forests and the forest sector. They can adversely affect tree growth and the yield of wood and non-wood products. Damage caused by forest pests can significantly reduce wildlife habitat thereby reducing local biodiversity and species richness. They can alter natural forest landscapes by decimating one or more tree species as has been observed in eastern American forests as a result of chestnut blight and throughout the Northern Hemisphere because of Dutch elm disease. Some pests have necessitated changes in management regimes often forcing forest managers to switch to alternative tree species in plantations; for example, the failed attempts in many parts of the world to establish mahogany plantations because of the presence of mahogany shoot borers ( Hypsipyla spp.). Pathogens may also limit the sites on which species can be grown successfully outside their natural range as has been experienced with red band needle blight (Mycosphaerella pini) and western gall rust (Endocronartium harknessii)infecting Pinus radiata.