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This study combined space syntax metrics and geographic information systems (GIS)-based built-environment measures to analyze pedestrian volume in different land-use zones, as recorded in unique public data from a pedestrian volume survey of 10,000 locations in Seoul, Korea. The results indicate that most of the built-environment variables, such as density, land use, accessibility, and street design measures, showed statistically significant associations with pedestrian volume. Among the syntactic variables, global integration showed a statistically significant association with the average pedestrian volume in residential and commercial zones. In contrast, local integration turned out to be an important factor in the commercial zone. Therefore, this study concludes that the syntactic variables of global and local integration, as well as some built-environment variables, should be considered as determinant factors of pedestrian volume, though the effects of those variables varied by land-use zone. Therefore, planning and public policies should use tailored approaches to promote urban vitality through pedestrian volume in accordance with each land-use zone’s characteristics.
