Frequent human activities have led to different types of land use conflicts which seriously restricted the multi-functional land use and the optimal allocation of resources. Optimizing the development and utilization pattern of land space, carrying out strategic layout, taking all aspects into consideration, and promoting green production and lifestyle are important measures to alleviate the contradiction between human and land and realize the harmonious coexistence between human beings and nature.

The change in land use leads to territorial spatial conflict. Territorial spatial conflicts mainly show that the boundaries of agricultural space, urban space, and ecological space overlap each other and interfere with each other’s functions, which will have a negative impact on regional high-quality development. The Aksu River, the most principal source of the Tarim River, the largest instream river in China, is a key area for maintaining ecological security in Northwestern China.

As China rapidly urbanizes, land resources tend to deplete. This paper aims to identify and propose a resolution of land use conflicts to promote sustainable land use and coordinate the interaction between humans and the environment in urban areas. The methodology of land use conflict assessment within spatial zoning of the Su–Xi–Chang region was evaluated. Taking into consideration the intensity of human activities and the background condition of the natural environment, we divided the study area into a few regions.