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The major objectives of this workshop are to sharpen the focus of ILRI's ecoregional research, to further identify commonalities in tools and new methods that can enable ILRI to do effective transregional research, and to identify improvements to the way in which ILRI does ecoregional research. Papers presented are on ILRI's research in the highland ecoregion; crop-livestock systems research in the Andean region; ecoregional research in South Asia and sub-humid West Africa; increasing productivity and sustainability of crop-livestock systems in semi-arid West Africa; ILRI's smallholder dairy systems research; integrating experiments with agronomic models and geographic information systems; integrating methodologies for analysing crop-livestock production systems; integrating remote sensing and dynamic models to assess pasture and livestock production at the ecoregional level - developments in the Altiplano; developing integrated models for application in crop-livestock systems; a decision support system to quantify trade-offs in sustainable agriculture and the environment in the Andes; system prototyping and simulation modelling in mixed farming systems; African highland initiative (AHI) and ICRAF research in Eastern and Central Africa; and global agro-climatic classification with emphasis on Asia.